VPD is a very interesting topic. It is a balance between temperature and pressure. All of what I've read on the subject talks about humidity as pressure and I'm not 100% that means barometric pressure as well. I am 100% positive that the only difference at the Mango Lights grow is the pressure. I won't see the results of Haze Garden 2.0 for a few weeks yet.
The symptoms were:
-Short,stunted, slow growth
-Susceptibility to mold
The experience is nothing like a nutrient deficiency or what not, it completely changes the way the plant grows. It's a super major factor.
The negative pressure imitates a high elevation which must affect plant mechanisms. Maybe the plant thinks it doesn't need a mold defense mechanism at that elevation. Exhausting air to manage humidity could actually make the problem worse if that is the case. We know that the plant prefers a tropical environment so why is humidity such a common problem?
IMO, it works like this, when you open the front door of your house, a breeze enters the room because the pressure in your house is lower than the pressure outside. So shouldn't you have the same effect when you open the door to your grow room? Picture a grow tent on the beach. If one of the doors were open, a mild breeze would inflate the tent. So a grow tent sitting in a room in your house should look inflated, right?
Peace.