Read this over the past three days off and on, I love dispelling b.s.!
There were quite a few things that made me laugh and scratch my head....
First being
[/QUOTQuote:
Originally Posted by Sam_Skunkman
G13 is not from University of Miss, I have been to the facility, I was invited to visit by Dr El Sohly , I asked them about G13 and they looked in their records and said they never had a plant called G13, they did not even have clones until a few yeas ago.
-SamS E
Well sam is just everywhere isnt he? lol, and I'm suprised that jesse didnt make a point of it. I wonder if sam bred the weed jesus christ of nazerath smoked? Either he is pure utter bullshit or he has alot of contacts with dea licenses.....same dude who gets so way bent out of shape everytime its mentioned he was busted.....
Oh and this made me laugh my ass off, this is what the u.s. government does with our favorite plant:
JIHA: What about the medical potential for Cannabis, either as whole drug or isolated products?
MAE: There is no question about the use of Cannabis for certain conditions. It does have a history. It does have the utility and so on. However, Cannabis as a smoked product, in my judgment, would not be a useful product simply because of the lack of standardization, the fact that it's a smoked material: you can't determine the dose, people smoke in different ways, plus the interaction of the many different components and degradation products, and the tars associated with smoked materials. So smoking is not a good delivery system. However, Cannabis as a plant that is rich in chemical components, would have potential for producing useful drugs, for example, THC. Now THC in the oral preparation, it doesn't seem to be doing the good job it should or was expected to. My personal view on the reason for this is the "first-pass effect". The material taken orally goes through the liver and is converted to the 11-hydroxy metabolite, which is 4-5 times more potent in terms of psychoactivity, before getting into the bloodstream, and the profile of these two drugs is quite different. Smoked material dosn't cause much of the 11-hydroxy metabolite to appear in the blood at all. You really only see THC and its inactive carboxy metabolite. Therefore, the pharmaco-logical profile of smoked material is the result of free THC in the blood. Suppositories were tried with THC and it didn't get absorbed at all, zero. So I took THC and converted it to a pro-drug that would be bioavailable from a suppository. Then, once it hits the bloodstream, it gets immediately converted to THC, which then mimics the smoked material. This had a number of advantages: number one, it avoids the "first pass effect" through the liver; number two, it never gives such a high level of THC all of a sudden, which gives a "rush" high that is normally associated with "abuse" and also paranoia for those people who are not used to the effect of THC, the overwhelming effect. Our dosage form gives a very subtle effect. If anything it's a more calming and sedating effoct that does not make the individual "lose touch with reality", and that blood level remains for quite a long time, it has a long plateau. Plus, it has a very quick onset of action, as compared to the oral. In 15 minutes, you see good measurable blood levels of THC, reaching a maximum at an hour, stays up there for 2, 3, 4 hours and then comes down again slowly. So it appears to me that what we ended up with is a preparation that you give as a suppository, but that doesn't have to be kept in the body for a long time, only 15-20 minutes. If you can retain it for 15-20 minutes, that's sufficient. The reason I say that, is that there was the concern about AIDS patients who might be suffering from diarrhea. There is diarrhea associated with that condition and if the person can keep the suppository in for 15 minutes, that's all you need to do. What happens is this drug almost gets sucked into the mucosa, maybe the fatty tissues of the intestine, and then it's a slow release into the bloodstream from that point on.
JIHA: Has any work been done on the anti-nausea, appetite stimulating properties or other potential medical uses of the 11-hydroxy compound?
MAE: No, not as much, no. The notion some people have that the action of smoked Cannabis is due to the 11-hydroxy metabolite, I honestly don't believe that, because in the blood stream you don't see much 11-hydroxy at all. When we developed our THC suppository, we did it with the idea of imitating smoking, without actually smoking. One option is to give it by injection. If you do, then you get the same profile as the smoked material, but people don't want to get a "shot". So the next choice is intradermal, a skin patch. But it doesn't work, THC just does not get absorbed through the skin.
Jesus Christ could they couldnt have made this up in a nazi brainstorming session.
I can imagine what this sick monster was saying in his presentation:
"I'll tell you what will keep those long haired faggots from abusing our medicine, we'll make them shove it up their ass!!"
"Plus i really hate lab monkeys and dogs too so I get to molest and torture a few thousand of them....and they think shots suck, zing!"
"And we came up with a formula that people can shoot themselves up with, all of our non-perscribed patients will just die of diseases so they won't make any bad press because who cares about junkie needle freaks..anyone?..nobody thats who!"
I mean seriously thats really fucked up!!! I understand that they want a scientifically pure way of dispension but even the good doctor himself states:
MAE:When we developed our THC suppository, we did it with the idea of imitating smoking, without actually smoking.
If it isnt broke don't fix it..........they have all types of expensive surgical disinfectants, what do they sometimes use for burn victims? MAGGOTS! Hey who out there is saying "yea sure throw some maggots on my open wounds"? But it WORKS. Check out the long term independent studies on the remaining NIDA research recipients on youtube, there was only one case of lung damage and it was stated that she/he smoked tobacco cigarettes.
Found this
amazingly funny:
JIHA: There are illegal, but unofficially tolerated, Cannabis "buyers' clubs" which have sprung up, some of which cater to thousands of patients. To implement the same thing on a more legitimate basis would require an expansion of the extiting federal "compassionate-use" program, which is now down to, I believe, 8 patients. Do you think that is feasible, if politically mandated?
MAE: First, let me comment on that program, which provides 300 cigarettes per month to a patient. In my judgment, that's way too much material for an individual to use for whatever condition. It's too much THC.[note by gertbfrow: the cannabis they recieve is between 3-4% end note.] I don't know how this was picked as the dose. But coming back to your question, if there is the political will to make it happen, it just means that NIDA will provide material for these clinical trials, because these are nothing but clinical trials.
I half agreed with him with the sheer amount of cannabis cigarettes being smoked (not vaporized) because of those suffering mouth,throat,nose,lung cancer could irritate already sensitive parts.
BUT WTF???:
MAE:It's too much THC. I don't know how this was picked as the dose."
What kind of sick twisted d.bag is this guy? Anal probes, injectable cannabis..... now the drug which he states:
MAE:Cannabis as a smoked product, in my judgment, would not be a useful product simply because of the lack of standardization, the fact that it's a smoked material: you can't determine the dose, people smoke in different ways, plus the interaction of the many different components and degradation products, and the tars associated with smoked materials. So smoking is not a good delivery system.
Well
gertbfrow didnt graduate from the University of Cairo OR University of Pittsburgh BUT wouldnt it make sense if what is qouted above is true and this is how the man really feels, than wouldnt it make sense to provide higher potency pot so that its smoked less often???? Has this guy ever spoken with a cannabis smoker about smoking cannabis? He's the g-damn director!
Maybe I can get a job as Director of Marijuana Research at Ole'Miss, with "state of the art" techniques that these hotshots just started using:
We have done one part of the garden, just all cuttings. And it works. We did cuttings of different plants and each group of cuttings came out exactly the same. I don't think it's unreasonable to do that. We would have to have a facility and a whole program to do it that way
HOLY(thisguyknowsnothingaboutmoderngrowing)BATMAN!
Even if this interview was done in the eighties which it wasnt, this guy
just started cloning here, just to find out...omg...that each group of cuttings came out exactly the same.
This right here folks, THIS is probally the BIGGEST indicator that the enigmatic G-13...DID NOT come from
this u.s. sanctioned marijuana research facility.
Is it as clear to everyone else as it is to me? If the cutting was only in cutting form, no seed, because IT WAS a cutting, and Ole'Miss just "discovered" cloning around the time of this article, than the cutting that nevil obtained most likley did not come
this facility.
On another note I watched a fox new special on the infamous research facilty and I've seen better grow-ops in person. PURE CRAP! It looked like nothing spectacular, and plus its all 2-3% weed anyways. All the plants were like 6' and no bud. The vids on youtube. But the nazi think tank probaly bred for low potentcy, lol.
Is anyone else feel kinda ripped off by the us govt's top research lab? I've personally put alotta money in that lab and what is to show for it? Every hard earned nickel taxed to death to fund this asshole's life? So they can gorw that shwag? I wasnt expecting any pineapple express operation but jesus. Its so pathetic, god from the d.bag in charge to their pot to their lack of any modern technique, I also saw the weed those poor 8 ppl that are left on the fantasy script of a lifetime's get.......I can buy the same for $200 1/4 pound. Dirt nasty crap! If only they took more time breeding for better tasting easier on the lungs, more potent weed that didnt require 10+ joints a day.
Has this asshole even taken a painkiller?? You dont give a terminally ill dying cancer paitent a tylenol #3, you dont give vicodin, you give them something strong enough that will last all day and night. They practically shove painkillers down your throat at the e.r. these days. I cut my eyeball and they asked what meds I was on, I told them suboxone for opiate addiction, she said "ok...well we're gonna give you some vicodin"....I didnt ask for any pain meds. Those meds robbed me of what I once knew as my life and my soul. I am now off all opiate meds after 6 years of shear hell. Is it clear to anyone else who doesnt want me to have safe non addictive medicine thats non-patentable? But god forbid I smoke some marijuana because if I live to be 200 I might get lung cancer from smoking cannabis.
Jesse as always your article is awesome, looks like you are a journalist afterall, not suprised in the least.
-peace
Nice thread as always. peace, resinbud
But I picked up where he left off with other strains. So I can totally see how the clone could totally be dead in NL. As my father's was nevils cross and it had degraded from 89', not 79'-82' or whenever ppl think nevil got it.
